In a significant move to raise awareness about a rare and challenging cancer that is on the rise, prominent buildings across the country will turn amber throughout August, recognized as Appendix Cancer Awareness Month. This initiative aims to shed light on appendix cancer, its increasing incidence, and the critical need for early detection and research. Appendix Cancer on the Rise...

We are proud to share new research led by our Scientific Advisory Board Chair, Dr. Andreana Holowatyj, and published in the Annals of Internal Medicine, finding that appendix cancer rates have quadrupled among Millennials. This landmark study, funded in part by The Appendix Cancer Research Foundation and the National Institutes of Health, was featured in The New York Times, TIME...

Patient Power recently invited cancer patients to share their individual thoughts, feelings, and experiences from diagnosis and beyond. The responses were then reported in the article below. They are all insightful and highlight the many challenges. Notably, the patient community as a whole reported many of the same perceptions and experiences. The responses are provided below. As we often say,...

Dr. Muhammad Talha Waheed, a postdoctoral research fellow at City of Hope, was recently interviewed by Cancer Network about study findings he first presented in a poster at the 2025 Society of Surgical Oncology (SSO) Annual Meeting. The research looks at the timing of surgery for appendix cancer and suggests a staged colectomy may be preferable in some cases. What...

Appendix cancer has often been treated like colorectal cancer (CRC). A recent article in ASCO Daily News by Dr. John Paul Shen, a member of ACPMP's Medical Advisory Board, and Dr. Michael B. Foote, explains why that approach deserves a closer look – and what it means for appendix cancer chemotherapy and future treatment. Key differences between appendix and colorectal...

Explore Our Refreshed and Expanded Clinical Trials Database ACPMP is excited to announce a significant update to our Clinical Trials Database – an important resource for physicians and their patients seeking clinical trials for appendix cancer. This update is part of our larger effort to provide the appendix cancer community with the most current and comprehensive information available. Here are...

The Appendix Cancer PMP Research Foundation (ACPMP) proudly announces the publication of a landmark article in Nature Reviews Cancer entitled “Defining a 'cells to society' research framework for appendiceal tumors.” This pivotal Expert Recommendation, officially published online on February 20, is the direct result of the Appendix Cancer PMP Research Foundation Scientific Think Tank—an innovative, multidisciplinary gathering designed to advance...

Thanks to the generosity of our donors, ACPMP is proud to fund two 2025 Society of Surgical Oncology (SSO) research grants focused solely on appendix cancer and PMP—including a significant new award in memory of our founder. SSO advances cancer research by providing research funding through its competitive Clinical Investigator and Young Investigator Awards programs. Introducing the Lisa Kurtz Luciano Appendix Cancer and Pseudomyxoma...

New research from MD Anderson Cancer Center, led by Dr. John Paul Shen – a member of ACPMP's Medical Advisory Board – finds that BRAF-mutant appendix cancer responds to BRAF-targeted therapy. The study was published in npj Precision Oncology. Why this research was needed Appendiceal adenocarcinoma is rare, and treatment options are limited. Historically, it has been treated with the...

February is recognized as National Cancer Prevention Month, an important time to discuss ways to reduce cancer risks and promote overall health. Yet, for appendix cancer—including Pseudomyxoma Peritonei (PMP)—no specific causes have been definitively identified. Below, we’ll explore what is currently known about appendix cancer, share general cancer prevention strategies recommended by leading authorities, and highlight the importance of ongoing...