Good News for Rare Disease Day and Every Day: Promising Lead on New Treatment for Pseudomyxoma Peritonei (PMP) — Written by: Deborah Shelton, ACPMP Executive Director

February 24, 2022

ACPMP Executive Director, Deborah Shelton, has over 25 years of experience providing regulatory advice to a diverse group of stakeholders navigating the complex landscape of scientific and clinical research directed at the development of treatments for cancer and a wide range of other conditions, with a particular focus on rare diseases. In research funded with grant support from the ACPMP Research...

“Diagnosis and Management of Acute Appendicitis in Adults” – Letter to the Editor & ACPMP Research Foundation Response

January 31, 2022

Please find below a Letter to the Editor written by Laura A. Lambert, MD, FACS, FSSO, on behalf of ACPMP’s Medical Advisory Board for the Appendix Cancer Pseudomyxoma Peritonei (ACPMP) Research Foundation. This letter was prompted by concerns raised to the organization by patients regarding the review article recently published in JAMA, titled “Diagnosis and Management of Acute Appendicitis in Adults”. Specifically, ACPMP patients...

The Unfolding Promise Of ctDNA – Written by: Deborah Shelton, ACPMP Executive Director

November 28, 2021

ACPMP Executive Director, Deborah Shelton, has over 20 years of experience providing legal counsel to clients navigating the complex regulations governing the testing and commercialization of FDA-regulated products, with a particular focus on pharmaceuticals and medical devices. Periodically provides insight on research topics of interest to our patient community. The Unfolding Promise Of cTDNA There are many promising scientific developments...

Reproductive Health After Cancer Diagnosis and Treatment Study

October 21, 2021

Dr. Andreana Holowatyj, Assistant Professor of Medicine at Vanderbilt University, is studying the impact of cancer, including appendix cancer, on reproductive health. She has a brief, confidential online survey (called the REACT Study). Dr. Holowatyj is a frequent collaborator with the ACPMP Research Foundation, and has served as a guest presenter for us --talking about the appendix cancer burden among adults...

Additional Step Forward for Genomic Sequencing

September 3, 2021

In another promising development for cancer patients, Foundation Medicine announced this week that it has partnered with Epic to integrate Foundation’s genomic sequencing program with Epic’s electronic medical record (EMR) system. This collaboration represents an exciting step for AC/PMP and other cancer patients by facilitating physicians’ capability of ordering, receiving, and reviewing results of the genomic sequencing of a patient’s...

FDA’s Accelerated Approval of Drug for Tumors With dMMR Deficiency (Advanced Solid Tumors)

August 19, 2021

We are pleased to report of a promising development for appendix cancer patients with a tumor identified as having a mismatch repair deficiency (or “dMMR”). This week, FDA granted accelerated approval for a drug to treat recurrent or advanced solid tumors having a dMMR for which patients have no satisfactory treatment options. Specifically, FDA has granted approval to GlaxoSmithKline’s drug...

WFORCE Publishes New Study on Organoids & Immunotherapy

July 16, 2021

The WFORCE team has released a new article in the journal Clinical Cancer Research titled “Organoid Platform in Preclinical Investigation of Personalized Immunotherapy Efficacy in Appendiceal Cancer: Feasibility Study.” The goal of this study was to “preclinically explore the application of immunotherapy in treating appendix cancer in a personalized organoid model.” The study showed that “[i]nformation derived from immunocompetent organoids...

Appendix Cancer Incidence Rising Among Young People

March 18, 2021

Yesterday, in a news story titled “Appendix Cancer Striking Young Patients” Robert and Angela Adams share their experience regarding Robert’s recent appendix cancer diagnosis. Robert is currently seeking treatment at Vanderbilt and hopes to have CRS/HIPEC soon following chemotherapy. “Doctors are seeing an increase in the number of patients with appendix cancer. Many of the patients are younger.”[1] Recently the Appendix Cancer...

Appendix Cancer is NOT the Same as Colorectal Cancer and Here’s Why

March 9, 2021

March is colorectal cancer awareness month. Colorectal cancer is the third most common cancer in the US, and the second leading cause of cancer death. It affects men and women of all racial and ethnic groups, and is most often found in people 50 years or older although incidence in those younger than 50 is on the rise.[1]. Appendix cancer...